GAT1 (SLC6A1) Transporter Assay

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GAT1 Transporter Assay Details
Relevance – Neurotransmission; validated therapeutic target
Single or Multi-Transporter Model – Single
Transporter Type – Uptake
Cell Model – MDCK-II
Assay Type – Intracellular accumulation
Exactly Matched Control Cells– Yes
Species – Human
Probe Substrate – GABA
Subcellular Localization in Assay Model – Apical
Inhibition Positive Control – Nipecotic acid