OATP1A2 (SLCO1A2) Transporter Assay

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OATP1A2 Transporter Assay Details
Relevance – Intestinal absorption; BBB penetration
Single or Multi-Transporter Model – Single
Transporter Type – Uptake Cell Model – MDCK-II
Assay Type – Intracellular accumulation
Exactly Matched Control Cells– yes
Species – Human
Probe Substrate – Estrone-3-sulfate
Subcellular Localization in Assay Model – Apical
Inhibition Positive Control – Bromosulfophthalein