xCT (SLC7A11) Transporter Assay

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xCT Transporter Assay Details
Relevance – Amino acid transport, anti-oxidative defense, neurotransmission
Single or Multi-Transporter Model – Single
Transporter Type – Uptake
Cell Model – MDCK-II
Assay Type – Intracellular accumulation
Exactly Matched Control Cells– Yes
Species – Human
Probe Substrate – Glutamic acid
Subcellular Localization in Assay Model – Basolateral
Inhibition Positive Control – Sulfasalazine