22nd North American ISSX Meeting

Visit BioIVT at booth # 407.

See our schedule of scientific contributions below.

Industry-Sponsored Symposium
Tuesday, July 17th, 7:30 – 8:30 am
Palais des congrès de Montréal, Room 210ae

Applications of a Micropatterned Co-Cultured (MPCC) Hepatocyte System to Support Small Molecule Drug Discovery

Speaker: T. Eric Ballard, Ph.D., Principal Scientist, Pfizer

Dr. T. Eric Ballard is a Principal Scientist in the Biotransformation group in Pharmacokinetics, Dynamics, and Metabolism at Pfizer.  In his current role, Eric investigates the clearance mechanisms and metabolism of small molecules and antibody-drug conjugates (ADCs) in support of early and late-stage research and development.  Eric has a particular interest in investigating tools to better detect reactive metabolites and their potential toxicity mechanisms.  Prior to his current position, Eric was a Postdoctoral Fellow in the Worldwide Medicinal Chemistry Group at Pfizer where he investigated the design and synthesis of clickable photoaffinity-based small molecule probes and their application to mechanism-of-action studies in neurologic and psychiatric disorders with Dr. Doug Johnson and Dr. David Gray.  Preceding his time at Pfizer, Eric was a Postdoctoral Associate in Prof. Timothy MacDonald’s lab at the University of Virginia where he worked on the synthesis of small molecule inhibitors of the PFOR enzyme present in anaerobic pathogenic bacteria. Eric received his Ph.D. in Organic Chemistry in 2008 from North Carolina State University under the direction of Prof. Christian Melander. He has coauthored over 30 publications on organic synthesis, bioorganic chemistry, chemical biology and biotransformation/metabolism.

Poster, #P50 
An Integrated In Vitro Screen Using Sandwich-Cultured Human Hepatocytes for Prediction of Cholestatic Hepatotoxicity
Presenter: 
Jonathan Jackson, Ph.D., BioIVT

 

Please join us at the 14th annual assembly of the HRA.

Tuesday, July 17th, 2:30 – 5:00 pm
Palais des congrès de Montréal, Room 511

P450 Enzyme Induction:  A Deeper Dive 
Learn more about using human and animal hepatocytes a way to directly communicate with each other and to share practical information on the use of hepatocytes.

Click here to register to attend.