Asian Conference on Drug-Drug Interactions (ADDI-2018)
December 3 – 6, 2018
See us at the ADDI-2018 conference.
Attend Dr. Kenneth Brouwer’s presentation, 6-Dec at 9:30 am entitled, Integrating BSEP Inhibition and FXR Mediated Regulation of Bile Acids to Improve Prediction of Cholestatic Drug-Induced Liver Injury. Dr. Brouwer, VP ADME Tox at BioIVT, will discuss advanced models to predict cholestatic hepatotoxicity that incorporate hepatocyte “adaptive response” to elevated bile acid concentration that can result from BSEP inhibition.