ASTERAND™ Human Liver Cancer Tissue

DISEASE FOCUS:Liver DiseaseOncology
FORMAT:FFPEFresh (cold)FrozenOCT Embedded
APPLICATION & SPECIALITY USES:Biomarker DiscoveryImmuno-oncologyPersonalized Medicine
Keywords:AdenocarinomaCholangiocarcinomaHepatocellular CarcinomaSquamous Cell Carcinoma



With access to both prospective and retrospective tissue collection, our bank of liver cancer tissue specimens offers immediate shipment of standard collections or the ability to collect specimens using research-based custom protocols. With available board certified pathology confirmation of disease and determination of percent tumor, necrosis, and inflammation, you have the guarantee of working with exactly the specimens your research requires. Standard and custom clinical data collection and confirmation ensures proper corresponding staging, treatment and outcome data.

Included Diagnoses

Adenocarcinoma (including all subtypes) and Squamous Cell Carcinoma (including all subtypes), Cholangiocarcinoma, Neuroendocrine Tumors of the liver, and Hepatocellular Carcinoma

Standard Biorepository Collections

Our readily available FFPE and Fresh Frozen samples are provided with clinical data that has been collected following a strict and standardized clinical data process. All specimens are reviewed for IRB approval and are assessed by our board certified pathologists to confirm diagnosis and quality. Some donors are available with associated blood-based biofluids.

Custom Collections

For more defined requirements, our personalized custom collection service office tissues collected to researchers’ specific needs. Samples can be collected in multiple preserved formats, including fresh and unpreserved. Tailored protocols, specific consent requirements and requisite accompanying clinical information are accommodated upon request. For custom request, please visit our custom product section.

Features & Benefits

  • Standard collection protocol across all prospective sites
  • Ethical collection of human specimens
  • Blinded IRB and Consent available for all specimens collected under IRB approval
  • Board-certified Pathology review of all tissue blocks
  • Clinical data review, including stage confirmation
  • Histological quality check of all tissue blocks
  • Multiple formats available: Mirrored, Matched, w/Adjacent Normal, Quad Set, with matched biofluids

This material should be handled as if capable of transmitting infectious agents. Please use universal precautions. No test method can provide total assurance that Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus, or other infectious agents are absent.

This product is being sold for research and/or manufacturing purposes only. It is not to be used in humans or animals and further manufacturing that will result in a finished product that contains viable cells is prohibited. For in vitro use only. The user assumes all responsibility for its usage and disposal, in accordance with all regulations.

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<li>Standard process requires that tissues are excised and processed with less than 30 minutes cold ischemic time.</li>
<li>Fixed samples are placed in 10% neutral buffered formalin for a minimum of 4 hours to ensure thorough fixation but no longer than 72 hours.</li>
<li>One section (minimum) is removed from each tissue block and stained with H&amp;E for quality review.</li>
<li>Tissue is evaluated by board certified pathologists to ensure tissue origin and diagnosis are consistent with clinical data.</li>
<li>Tissue quality and integrity is characterized for paraffin quality, tissue size and processing quality.</li>
<li>Sample Level Tumor (STMR) is determined for malignant samples.</li>
<li>Normal tissue cellular composition is evaluated to estimate&nbsp;percentage(%) of parenchyma present in the sample.</li>
<li>BioIVT upholds the fundamental bioethics principles of autonomy, privacy, safety and informed consent. We support legal and ethical efforts to promote voluntary donation of surplus human tissues and clinical information for research use. In general, the tissue BioIVT receives is surplus surgical tissue that would otherwise be discarded following surgery performed for medical treatment.&nbsp; BioIVT maintains a global network of collaborators who conduct subject recruitment, informed consent and scientific activities. We ensure that all of our activities, and those of our collaborators, are conducted in accordance with applicable laws, regulations, and ordinances. BioIVT confirms that the following activities have been completed by our collaborators (as necessary): institutional and independent review board approval, privacy officer authorization, government licenses, or industry accreditations. We continually monitor our practices to conform to evolving external scientific, legal and ethical requirements.</li>