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A unique reagent to prevent heterophilic antibody interference in immunoassays, Immunoglobulin Inhibiting Reagent (IIR) is a formulation of immunoglobulins that is specifically targeted against heterophilic antibodies to block their interference in immunoassays. IIR is not precipitated IgG. Because of it’s unique formulation and it’s purity (>96%), IIR may be used at extremely low concentrations without any effect on dilutions or recovery.
IIR has an extremely high binding affinity which enables it to inhibit the action of human heterophilic antibodies. The affinity value of human heterophilic antibodies is in the order of 106 Litres/Mol. Immunoglobulin Inhibiting Reagent (IIR) has a binding affinity which exceeds 109 Litres/Mol. This greatly enhanced binding affinity ensures that heterophilic interference is virtually eliminated.
To read more about use of this reagent, click here.
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