LIVERPOOL Cryopreserved Hepatocytes

Type:Cell Products
APPLICATION & SPECIALITY USES:ADME-Toxicology Products and Services



Our best-selling, patented LIVERPOOL® pooled human hepatocytes are designed exclusively by BioIVT to have the characterization, quality and viability you need for your research. Read our scientific poster on how we developed LIVERPOOL using a predictive algorithm to target specific metabolic activity.

To produce LIVERPOOL, all incoming donor tissue and combined lots are characterized using our proprietary algorithm. The hepatocytes are derived from only high-quality, non-transplantable liver tissue from fresh, whole livers. Their viability is greater than 80% and the cells exhibit both phase I and II enzyme activities.

Order any of our standard pooled samples, or we can custom-blend donor lots from the world’s largest cryopreserved hepatocytes inventory to meet your exact specifications. To customize a LIVERPOOL human hepatocyte lot for your research fill out the Request a Quote form.

Features and Benefits

  • Purpose-Pooled. A proprietary algorithm, drawing up a cell database of known substrate performances, selects hepatocyte lots from a well-characterized cell bank to achieve targeted enzyme levels
  • Characterization: All LIVERPOOL products are fully characterized across numerous substrates to ensure consistency and reliability
  • Format Choice: Available in 5-, 10-, 20-, 50- and 200-donor pool sizes
  • Savings. In both time and money, LIVERPOOL hepatocytes enable researchers to eliminate pooling procedures, characterization testing and costly multi-donor work
  • Large Lot Sizes. All contributory hepatocyte lots are sourced from whole, intact, transplant-quality livers, ensuring each donor lot can create large product sizes. This enables researchers to have great consistency across multiple experiment
  • Quality, All LIVERPOOL lots must meet and exceed stringent quality control specifications prior to release.
  • Custom Product Design. The LIVERPOOL Purpose-Pooling technique allows researchers to order specific product specifications and donor pool sizes and creates custom products to suit

The process for producing the LIVERPOOL pooled human hepatocyte products is covered by one or more U.S. or foreign patents and patent applications, including U.S. Patent No. 7,604,929.

Caution: Treat all products containing human materials as potentially infectious, as no known test methods can offer assurance that products derived from human tissues will not transmit infectious agents.

All products are for research use only. Do not use in animals or humans. These products have not been approved for any diagnostic or clinical procedures.

Cryosuspension human hepatocytes are >80% viable and contain a minimum of 5 million cells per vial as determined by Trypan Blue exlcusion.

BioIVT provides’ technical support to our customers and this support includes onsite demos or training for handling our hepatocyte, microsome and S9. We have a group of Scientific Advisors that regularly visit customers to discuss their research and ongoing studies. If there are any questions or concerns about the use of our products or a protocol contact our Scientific Advisors for additional help.