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A deeper understanding of the pathobiology of cancer has brought into the forefront the importance of tumor mutation status and the critical role these mutations may play in disease progression. Mutation analysis is now being used as a diagnostic tool for diseases beyond cancer, used in basic research as well as in drug and diagnostic development. BioIVT performs both standard mutation analysis for lung, melanoma and colon and custom mutation screens on both tissues and biofluids.
As technology advances, scientists will expand their ability to analyze vast amounts of data as well as detect minute amounts of biomarkers. Understanding how miRNAs, metabolomics, and driver mutations can be used for early detection of disease, contribution to disease development/severity as well as effect response to medication and treatment, will result in faster and better diagnosis and treatment options. One of the most important factors in being able to design an assay is having enough of the right samples. BioIVT, with its extensive network of over 200 IRB approved collection centers, is able to partner with you to obtain the samples required for assay development. In addition, we can provide those samples with the associated clinical data necessary to move your research forward.
BioIVT offers custom screening of banked inventory or custom collections using qPCR, Sanger/Pyrosequencing, Next Generation Sequencing (NGS), IHC or FISH. With our ready access to large cohorts of human tissues, we offer the expertise of experimental design, execution and management of your project.
BioIVT offers FFPE and frozen tumor specimens of which we test for mutations relevant to cancer research. The tested specimens include:
These specimens are available for immediate shipment and include tumors with both mutated and wild-type status. Furthermore, donor-matched serum and plasma are also available.
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