Single-Transporter Assays

Type:Services
SUBTYPE:Transporter Assays
APPLICATION & SPECIALITY USES:ADME-Toxicology Products and Services
Keywords:DDIRegulatoryTransporters

With over 100 assays we offer the largest selection of single-transporter assays in the industry. Our extensive portfolio of assays is made possible through the use of OPTI-EXPRESSION™ Technology, which allows the transient transfection of polarized cell monolayers and has the folowing benefits:

  • Consistent expression of the transporter of interest
  • Localization of the transporter to the appropriate (i.e., physiologically-relevant) membrane (i.e., apical or basolateral)
  • Exactly matched controls
  • Ability to control protein expression levels to mimic those seen in vivo
  • Ability to develop new assays much more quickly than is possible by conventional methods.

Our clients rely on our single-transporter assay services to provide insight into the transporters involved in the pharmacokinetic activity of xenobiotics and endogenous ligands. Our portfolio of single transporter assays is listed below. Additionally, we offer Custom Development services to design and develop new transporter assays using OPTI-EXPRESSION Technology.

 

Single-Transporter Assays A-Z
TransporterGene
ASBTSLC10A2
asc-1

SLC7A10
ASCT2SLC1A5
ATB0+SLC6A14
BAT1 (CSNU3)SLC7A9
BCRPABCG2
BSEPABCB11
CAT1SLC7A1
CAT2BSLC7A2
CAT3SLC7A3
CHTSLC5A7
CNT1SLC28A1
CNT2SLC28A2
CNT3SLC28A3
CRTSLC6A8
DATSLC6A3
EAAT1SLC1A3
EAAT2SLC1A2
EAAT3SLC1A1
ENT1SLC29A1
ENT2SLC29A2
ENT4SLC29A4
GAT1SLC6A1
GAT2SLC6A13
GAT3SLC6A11
GLYT1SLC6A9
GLYT2SLC6A5
LAT1SLC7A5
MATE1SLC47A1
MATE2-KSLC47A2
MCT1SLC16A1
MRP1ABCC1
MRP2ABCC2
MRP3ABCC3
MRP4ABCC4
NETSLC6A2
NTCPSLC10A1
OAT1SLC22A6
OAT2SLC22A7
OAT3SLC22A8
OAT4SLC22A11
OATP1A2SLCO1A2
OATP1B1SLCO1B1
OATP1B3SLCO1B3
OATP2B1SLCO2B1
OCT1SLC22A1
OCT2SLC22A2
OCT3SLC22A3
OCTN1SLC22A4
OCTN2SLC22A5
OSTα-OSTβSLC51A1 / SLC51A2
PAT2SLC36A2
PCFTSLC46A1
PEPT1SLC15A1
PEPT2SLC15A2
P-gpABCB1 (MDR1)
PROTSLC6A7
RFCSLC19A1
SERTSLC6A4
SGLT1SLC5A1
SGLT2SLC5A2
SMVTSLC5A6
SNAT1SLC38A1
SNAT2SLC38A2
THTR1SLC19A2
THTR2SLC19A3
URAT1SLC22A12
xCTSLC7A11