With over 100 assays we offer the largest selection of single-transporter assays in the industry. Our extensive portfolio of assays is made possible through the use of OPTI-EXPRESSION™ Technology, which allows the transient transfection of polarized cell monolayers and has the folowing benefits:
- Consistent expression of the transporter of interest
- Localization of the transporter to the appropriate (i.e., physiologically-relevant) membrane (i.e., apical or basolateral)
- Exactly matched controls
- Ability to control protein expression levels to mimic those seen in vivo
- Ability to develop new assays much more quickly than is possible by conventional methods.
Our clients rely on our single-transporter assay services to provide insight into the transporters involved in the pharmacokinetic activity of xenobiotics and endogenous ligands. Our portfolio of single transporter assays is listed below. Additionally, we offer Custom Development services to design and develop new transporter assays using OPTI-EXPRESSION Technology.
Single-Transporter Assays A-Z